N.D. This test was not done. Antigen and antigen domain used for selection are indicated along with the number of binding mAbs, the number of unique mAbs, and the number of mAbs binding mammalian cell
These are the raw reads for an antibody library screened against dozens of variants of the SARS-Cov2 / COVID-19 spike protein RBD to identify tight binders with broad-spectrum activity.
Out of 994 sequenced phage clones, 557 intact scFv sequences were derived, among which 166 diverse scFv sequences were identified (see S2 Table).a Frequency of unique scFv antibody sequencesb Number o
We generated LNP-mRNA encoding B.1.1.529 SARS-CoV-2 spike, and intramuscularly administered it in a human IgG and IgK knock-in mouse. Single cell VDJ-seq unveiled the sequences of human monoclonal ant