Multi-omics analysis identifies erythroid cells as the major population in mouse placentas expressing the MHC class II antigen presentation, chemokine, and antibacterial immune response genes [Nanostring]

Pregnancy is one of the most important processes for mammals, which is deeply controlled by the immune system. We performed NanoString Immune Transcriptome to profile erythroid cells from mouse placentas from semi-allogeneic and syngeneic pregnancies at E12.5 and E19.5 to elucidate the differences between these types of pregnancies. We collected murine placentas at E12.5 and E19.5 from both syngeneic and semi-allogenic pregnancies, extracted Ter-119 Erythroid cells and performed NanoString Immune transcriptome analysis