Systemic Complications of Streptococci in Chronic Tonsillitis: Case Series

Streptolysin O is one of the toxins produced from Group A Beta Hemolytic Streptococcal
(GABHS) infection. In the human body infected with GABHS will produce a natural
antigen, namely anti-Streptolysin titer O (ASTO). [1] Throat culture is performed to
determine the presence of group A Streptococci in the upper respiratory tract. Throat
cultures have a sensitivity of about 90% - 95% in detecting the presence of GABHS. The
purpose of writing this case report is to provide knowledge to peers about systemic
complications resulting from Streptococcal infection in tonsillitis. It has been reported in
all five cases mentioned above with an increase in ASTO titer >200 IU/ml. Of the five
patients experienced complications due to Streptolysin toxin, endophtalmitis, rheumatoid
arthritis and endocarditis. While from the examination of tonsil culture found Candida sp.,
Enterococcus faecalis, Enterobacter aerogenes.

链球菌溶血素O为A群β溶血性链球菌（GABHS）感染所产生的一种毒素。在感染GABHS的人类体内，将产生一种天然抗原，即抗链球菌溶血素O抗体滴度（ASTO）。[1] 气管培养用于检测上呼吸道中是否存在A群链球菌，其检测GABHS存在的灵敏度约为90% - 95%。撰写本病例报告的目的是向同行提供关于扁桃体炎中链球菌感染所致全身性并发症的知识。在上述提到的五个病例中，均出现了ASTO滴度大于200 IU/ml的升高。在这五位患者中，因链球菌溶血素毒素而出现并发症者，包括眼内炎、类风湿性关节炎和心内膜炎。同时，通过对扁桃体培养的检查，发现存在念珠菌属、粪肠球菌、产气肠杆菌。