Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0020187
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Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0020187 Descriptor: Arginase-2, mitochondrial, Fab C0020187 heavy chain (IgG1), ... Authors: Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. Deposit date: 2019-09-06 Release date: 2020-06-10 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation. Proc.Natl.Acad.Sci.USA, 117, 2020
结合抑制性人源抗原结合片段(Fab)C0020187的精氨酸酶-2晶体结构
描述项:线粒体精氨酸酶-2、Fab C0020187重链(免疫球蛋白G1,IgG1),……
作者:Burschowsky, D、Addyman, A、Fiedler, S、Groves, M、Haynes, S、Seewooruthun, C、Carr, M
提交日期:2019-09-06
发布日期:2020-06-10
最后修改日期:2024-10-23
实验方法:X射线衍射(3.25 Å)
引用文献:通过非定向亲和力成熟策略实现精氨酸酶2抑制性抗体的广泛序列与结构进化。《美国国家科学院院刊》,117卷,2020年
创建时间:
2019-09-06



