Conformational Studies by Dynamic NMR. 100. Enantiomerization Process of Stereolabile Atropisomers in Pyridine-Substituted Adamantane Derivatives
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https://figshare.com/articles/dataset/Conformational_Studies_by_Dynamic_NMR_100_Enantiomerization_Process_of_Stereolabile_Atropisomers_in_Pyridine_Substituted_Adamantane_Derivatives/3327880
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资源简介：
The barriers for interconverting the conformational enantiomers (stereolabile atropisomers) of pyridine-substituted adamantane derivatives have been determined
by dynamic 13C NMR spectroscopy. The trend of these values
parallels that anticipated by MM calculations. In at least
one case, the computed structure was found to agree with
that obtained by single-crystal X-ray diffraction. In addition,
it has been possible to achieve a physical separation of a
pair of these stereolabile atropisomers at −60 °C by means
of the enantioselective cryogenic HPLC technique.
创建时间：
2004-08-20
