Ageing of the hematopoietic stem cell (HSC) compartment is characterized by skewing towards the myeloid lineage and reduced stem cell function, the molecular basis of which is largely unknown. Using s
The impact of aging on intestinal stem cells (ISCs) has not been fully elucidated. In this study, we identified widespread epigenetic and transcriptional alterations in old ISCs. Using a reprogramming
The aging of hematopoietic stem cells (HSCs) significantly alters their characteristics. Mitochondria, essential for cellular metabolism, play a crucial role, and their dysfunction is a hallmark of ag
Additional file 6. Table S3. List of transcripts of 120210 genes and their FPKM from transcriptome sequence in UMSC-P4 and UMSC-P9. Related to Figure 7A and 7B.
