Aiming to explore the temporal stability of gut microbiota in Parkinson's disease and the potential relationship of microbiota and disease progression, we characterized the gut bacterial communities o
Non-motor symptoms are clinical manifestations of amyotrophic lateral sclerosis (ALS). However, few studies have examined these symptoms in patients with early-stage ALS. We conducted a cross-sectiona
We sequenced the V3-V5 hypervariable region of the bacterial 16S rRNA gene in DNA derived from 631 CF sputum specimens collected from 111 subjects over 10 years. We observed fluctuations in the abunda