WP2583 - T cell receptor and co-stimulatory signaling - Homo sapiens
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ndexbio.org/viewer/networks/13b30225-5c6a-11ec-b3be-0ac135e8bacf
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资源简介：
The activation and translocation of transcription factors NFAT, AP-1 and NF-kappa-B via the co-stimulatory signaling cascade triggered by MHC peptide, B7 proteins and PD-L1. The activation of NFAT involves a Ca2+/calcineurin disruption of a massive RNA-protein complex prior to its translocation into the nucleus and ultimate transcription factor activity.
Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP2583).
创建时间：
2025-04-17
