Neisseria gonorrhoeae whole genome sequencing. Neisseria gonorrhoeae

Gonorrhoea is a grave public health problem globally. China has a high burden of gonorrhoea. The number of reported new cases of gonorrhoea in China increased dramatically from 100,245 to 115,024. The increase of reported new gonorrhoea cases in China is related to several factors, one of which is antimicrobial resistance (AMR). AMR in China was monitored by China Gonococcal Resistance Surveillance Program (GRSP), which is part of WHO west pacific region gonococcal antibiotic resistance surveillance program (WHO WPRO GASP). Here, we performed WGS in N. gonorrhoeae clinical isolates collected from China GRSP sentinel sites to identify the predominant strains spread in China and compare the characteristics of these isolates with strains isolates in the world.