In-depth profiling of transcriptional activity of Aire in mouse mTECs
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https://www.ncbi.nlm.nih.gov/sra/SRP416153
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资源简介：
Aire, a transcriptional regulator whose defect results in the development of autoimmunity, controls the transcriptome in medullary thymic epithelial cells (mTECs) including the genes for self-antigens. Here, we utilized a technique for profiling transcriptome from a single cell (RamDA-seq) to investigate bulk populations in mTECs deeply. Overall design: Bulk RNA-seq analysis of FACS-sorted mouse thymic epithelial cells (TECs, CD45-EpCAM+Ly51-) from wild-type and Aire knockout (KO) mice
创建时间：
2023-04-09
