Candidates of Helicobacter pylori antigenic proteins recognized by IgG antibodies in sera of Japanese H. pylori-positive children as determined by LC-MS/MS.

1) Protein names with * are newly identified H. pylori antigenic protein candidates in this study. Abbreviated names are indidcated in parentheses.Alternative name is indicated after/. W38, W57 and W69 spots included two antigen candidate proteins with high MS scores.2) Proteins which were identified from more than two distinctive peptides by Spectrum Mill MS Proteomics Workbench, except W2 and W15.3) Proteins which were identified as more than 20 MS/MS Search Score by Spectrum Mill MS Proteomics Workbench, except W2 and W15.4) SP: Swiss Prot, EA: East-Asia 7 strains, othrers are all by NCBI.5) Identification by immunoblot analysis using wild type and knockout strains of the coressponding genes.6) FlaA was also reacted with two of H. pylori-negative child serum samples, not included in this number**.