Human Protein Atlas - Single cell

The Single Cell resource of the Human Protein Atlas presents comprehensive data on gene expression across various human tissues and cell types, utilizing single cell RNA sequencing (scRNAseq), cell sorting, single nuclei RNA sequencing (snRNAseq), and bulk RNAseq correlation analyses. The resource provides insights into mRNA and protein expression patterns, gene specificity, and expression clustering with single cell types, immune cells and brain single nuclei. The Single Cell Resource includes four main datasets:

The Single cell type section, providing the expression profiles across 81 cell types from 31 human tissues, and cell type specificity based on gene expression.
The Tissue cell type section, providing the predicted cell-type expression specificity based on bulk RNAseq
The Single nuclei brain section, providing more details regarding cell type specificity within the brain, based on single nuclei RNAseq
The Immune cell section, providing expression comparison between sorted immune cells

Learn more about each of these four parts down below, and explore the details of each dataset, or serach for a gene and browse the expression details side by side across the different datasets on the gene summary pages. More information about the content, the generation and analysis of the data in this resource can be found under respective link or here for single cell type, tissue cell type, single nuclei brain and immune cell. Additionally, each focused section is based on different datasets, see more details here for single cell type, tissue cell type (using GTEx RNAseq data), single nuclei brain and immune cell.

人类蛋白质图谱的单细胞资源全面展示了不同人类组织和细胞类型中基因表达的详尽数据，通过单细胞RNA测序（scRNAseq）、细胞分选、单个核RNA测序（snRNAseq）以及总RNA测序相关性分析等方法获取。该资源为mRNA和蛋白质表达模式、基因特异性以及单细胞类型、免疫细胞和大脑单个核的表达聚类提供了洞见。单细胞资源主要包括以下四个主要数据集：

- 单细胞类型部分，提供了来自31个人类组织中81种细胞类型的表达谱，以及基于基因表达的细胞类型特异性。
- 组织细胞类型部分，提供了基于总RNA测序预测的细胞类型表达特异性。
- 单个核大脑部分，基于单个核RNA测序提供了关于大脑中细胞类型特异性的更多细节。
- 免疫细胞部分，提供了分选免疫细胞之间的表达比较。

以下将详细介绍这四个部分，并探索每个数据集的详细信息，或通过基因摘要页面搜索基因并浏览不同数据集中基因表达详情。关于该资源内容、数据生成和分析的更多信息，可在相应链接或以下链接中找到：单细胞类型、组织细胞类型（使用GTEx RNAseq数据）、单个核大脑和免疫细胞。此外，每个专注部分基于不同的数据集，更多详细信息请见以下链接：单细胞类型、组织细胞类型（使用GTEx RNAseq数据）、单个核大脑和免疫细胞。