D221(169)N MUTANT DOES NOT PROMOTE OPENING OF THE COFACTOR IMIDAZOLIDINE RING

NIAID Data Ecosystem2026-05-02 收录

酶催化机制

蛋白突变效应

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D221(169)N MUTANT DOES NOT PROMOTE OPENING OF THE COFACTOR IMIDAZOLIDINE RING

创建时间：

2024-10-30

Structure of alpha-1,3-glucanase agn1

蛋白质结构解析

酶催化机制

Structure of alpha-1,3-glucanase agn1 Descriptor: Glucan endo-1,3-alpha-glucosidase agn1 Authors: Horaguch, Y, Yano, S, Makabe, K. Deposit date: 2024-02-24 Release date: 2025-02-26 Last modified: 2026

Protein Data Bank Japan2026-03-11 更新20

How important are entropic contributions to enzyme catalysis?

酶催化机制

熵效应计算模拟

The idea that enzymes accelerate their reactions by entropic effects has played a major role in many prominent proposals about the origin of enzyme catalysis. This idea implies that the binding to an

PubMed Central2000-10-24 更新10

Cryo-EM Structure of Sf9 produced recombinant N-acetyltransferase 10 (NAT10) in complex with cytidine-amide-CoA bisubstrate probe and ADP/Mg2+.

蛋白质结构解析

酶催化机制

Cryo-EM Structure of Sf9 produced recombinant N-acetyltransferase 10 (NAT10) in complex with cytidine-amide-CoA bisubstrate probe and ADP/Mg2+.

NIAID Data Ecosystem00

A Thiamine-Dependent Enzyme Utilizes an Active Tetrahedral Intermediate in Vitamin K Biosynthesis

维生素K生物合成

酶催化机制

Enamine is a well-known reactive intermediate mediating essential thiamine-dependent catalysis in central metabolic pathways. However, this intermediate is not found in the thiamine-dependent catalysi

NIAID Data Ecosystem20

Structure of Gan1D-E170Q, a catalytic mutant of a putative 6-phospho-beta-galactosidase from Geobacillus stearothermophilus

蛋白质结构解析

酶催化机制

Structure of Gan1D-E170Q, a catalytic mutant of a putative 6-phospho-beta-galactosidase from Geobacillus stearothermophilus

NIAID Data Ecosystem10