RNA Sequencing Analysis of wild type (WT) and Mrp4 knock out (Mrp4-/-) mice adipose tissue Transcriptomes

The goal of this study is to idenitfy the role of multi drug resistance-associated protein- 4 ( Mrp4), a drug transorter, in adipose tissue phyisiology and adipogenesis processes. In this study we aim to identify gene expression changes in adipose tissue that are altered due to lack of Mrp4 in mice. These gene expression changes observed will aid us in idenitifying the role of Mrp4 in adipose tissue physiology and its role in adipogenesis processes. Overall design: We have analysed white adipose tissue mRNA profiles of 16 week old wild type (WT) and Mrp4 knock out (Mrp4-/-) mice. In this experiment we have n=4 samples per genotype