Enantioselective Synthesis of Carbo- and Heterocycles through a CuH-Catalyzed Hydroalkylation Approach
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https://figshare.com/articles/dataset/Enantioselective_Synthesis_of_Carbo_and_Heterocycles_through_a_CuH_Catalyzed_Hydroalkylation_Approach/2137795
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资源简介：
The enantioselective, intramolecular
hydroalkylation of halide-tethered
styrenes has been achieved through a copper hydride-catalyzed process.
This approach allowed for the synthesis of enantioenriched cyclobutanes,
cyclopentanes, indanes, and six-membered N- and O-heterocycles. This
protocol was applied to the synthesis of the commercial serotonin
reuptake inhibitor (−)-paroxetine.
创建时间：
2016-08-09
