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资源简介：
Paneth cell-related genes.
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创建时间：
2022-04-06
相关数据集
Loss of Sirt1 Function Improves Intestinal Anti-Bacterial Defense and Protects from Colitis-Induced Colorectal Cancer
Dysfunction of Paneth and goblet cells in the intestine contributes to inflammatory bowel disease (IBD) and colitis-associated colorectal cancer (CAC). Here, we report a role for the NAD+-dependent hi
NIAID Data Ecosystem50
Intestinal antiviral signaling is controlled by autophagy gene Epg5 independent of the microbiota. Epg5
Mutations in the autophagy gene EPG5 are responsible for Vici syndrome, a human genetic disease characterized by combined immunodeficiency. Previously, we found that a mutation in Epg5 in mice is asso
NIAID Data Ecosystem30
Smarcad1 coordinates innate immunity-linked gene expression in the intestinal epithelium [ChIP-seq]
How intestinal epithelial cells interact with the host immune system and the microbiota and how this is regulated at the gene expression level are critical questions. Smarcad1 is one of the most conse
NIAID Data Ecosystem10
MicroRNA-802 regulates the innate immune response through Paneth cell expansion and Wnt signaling. MicroRNA-802 regulates the innate immune response through Paneth cell expansion and Wnt signaling
Paneth cells are important for maintaining epithelial cell renewal and modulating innate immune function in the intestine through secretion of growth factors and antimicrobial peptides, which help sus
NIAID Data Ecosystem30
Ileal gene expression in Duoxa-/- mice and cohoused littermate controls. Mus musculus
Dual oxidases play a role in innate host defense at barrier epithelia. We examined the effect of loss of dual oxidase function (duoxa-/-) on gene expression in the mouse terminal ileum at homeostasis.
NIAID Data Ecosystem20
