Modeling of the SEA complex, a modulator of the TORC1 pathway

These scripts demonstrate the use of IMP, MODELLER, and PMI in the modeling of the SEA complex using 188 DSS chemical cross-links and 23 composites from affinity purification.

First, MODELLER is used to generate initial structures for the individual components where reliable templates are available. Then, IMP / PMI are used to model these components using the DSS crosslinks and the affinity purification data for the entire SEA complex.

For more information about how to reproduce this modeling, see https://salilab.org/sea or the README file.