Adaptive Hybrid of Color Doppler and Ultrasound Speckle Image Velocimetry for the Accurate Measurement of Blood Flow

In this study, adaptive hybrid (AH) scheme is proposed to enhance the measurement accuracy of conventional CD method to acquire the 2-dimensional velocity field of blood flows. It can offer the assistance of the velocity field information measured preliminarily using ultrasound speckle image velocimetry (SIV) technique. Consequently, erroneous vectors in the CD results were replaced with the SIV results. The performance of the proposed AH method was validated by varying flow rate and insonation angle. We compared the AH method with the CD and SIV methods in an agarose vessel model. In vitro validation experiment demonstrated that the proposed AH method can measure a 2-dimensional velocity field with improved accuracy. In vivo validation was conducted for venous flow in the human great saphenous vein. These datasets offer the in vitro and in vivo experimental results for the validation of its performances. The AH method was confirmed by checking constant volumetric flow rate under in vivo conditions.

本研究提出了一种自适应混合（AH）方案，旨在提升传统CD方法在获取血流二维速度场时的测量精度。该方案能够借助超声斑图图像速度测量（SIV）技术所初步测量的速度场信息提供辅助。因此，CD结果中的错误向量被SIV结果所替代。通过改变流速和超声入射角，验证了所提出的AH方法的有效性。在明胶血管模型中，将AH方法与CD和SIV方法进行了比较。体外验证实验表明，所提出的AH方法能够以更高的精度测量二维速度场。在人体大隐静脉中的静脉血流进行了体内验证。这些数据集提供了体外和体内实验结果，以验证其性能。通过检查体内条件下的恒定体积流量，验证了AH方法的准确性。