EZH2 and JARID2 change their binding profiles on RNA and DNA to promote hepatocellular carcinoma

NIAID Data Ecosystem2026-03-13 收录

癌症分子机制

表观遗传调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE133984 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2022-07-04

DataSheet4_PRR11 promotes cell proliferation by regulating PTTG1 through interacting with E2F1 transcription factor in pan-cancer.zip

癌症分子机制

细胞周期调控

The upregulated proline rich 11 (PRR11) plays a critical role in cancer progression. The relevant biological functions of PRR11 in pan-cancer development are not well understood. In the current study,

NIAID Data Ecosystem30

ChIP Seq of influenza specific primary, memory and secondary CD4+ T cells [InVitro]

表观遗传调控

CD4+T细胞记忆

Immune responses to infection involve a careful balance: too weak a response allows pathogen replication; too strong risks immunopathology. The immunoregulatory cytokine IL-10 is a key factor in this

NIAID Data Ecosystem00

ZDHHC15 mediates Hippo/YAP pathway palmitoylation and regulates tumor progression [TOV-112D]. ZDHHC15 mediates Hippo/YAP pathway palmitoylation and regulates tumor progression [TOV-112D]

表观遗传调控

YAP信号通路

The Post-translational modification of Hippo/YAP pathway members plays an important role in regulating the activation of Hippo/YAP pathway and its effects in tumors. S-Palmitoylation, also known as S-

NIAID Data Ecosystem00

Multimodal learning of noncoding variant effects using genome sequence and chromatin structure

变异功能预测

表观遗传调控

ncVarPred-1D3D: pretrained models of Sei (PMID: 35817977) + our 3D structure embedding models are shared. The models are trained and validated using DeepSEA (PMID: 26301843) selected 200 bp regions (w

Zenodo2023-08-08 更新00

DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

表观遗传调控

甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

EZH2 and JARID2 change their binding profiles on RNA and DNA to promote hepatocellular carcinoma

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