Characteristics of airway microbiota might influence asthma status or asthma phenotype. Our goal was to identify airway microbiome and to investigate the role that microbiome played in asthma phenotyp
The five most significantly down- and up-regulated gene sets among the MSigDB canonical pathways, Gene Ontology categories, and motif gene sets are shown, ordered in each subsection by CAMERA p-value.
We present evidence that (1) viral respiratory infections are potential mechanisms of ACE2 overexpression in patients with asthma and (2) ACE activation regulates multiple cytokine anti-viral response
Additional file 2: Table S1. Subjects’ demographics with the calculations of averages and their standard deviation (SD). The counts of different cells were calculated in 200 μL BALF.
In this study, we will enroll allergic adults to undergo bronchoscopic segmental allergen challenge, in order to identify differences in the airway immune response to allergen in those with asthma com