A proteomic platform unveils PGK1 and 2 as potential target for Tatridin A
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https://www.omicsdi.org/dataset/pride/PXD034940
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资源简介:
A multi-disciplinary strategy has been developed and applied for identifying Tatridin A target(s) to fully address its mechanism of action, based on drug affinity response target stability and targeted limited proteolysis. Both approaches point to the identification of PGK 1 and 2 (phospoglicerate kinase 1 and 2) as major Tatridin A targets in THP-1 cell lysates, giving also detailed insights into the ligand/proteins interaction sites.
创建时间:
2023-07-31



