Mapping polymerase usage by tracking ribonucleotide incorporation (HydEn-seq) during DNA replication
收藏NIAID Data Ecosystem2026-03-11 收录
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资源简介：
We devised and improved on our hydrolytic end sequencing (HydEn-seq) that mapping ribonucleotide incorporation in genome and used this method to track DNA replicative polymerase usage. We uncovered striking exceptions to canonical polymerase division of labor in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Examination of location of ribonucleotides in multiple yeast strains bearing different DNA polymerase variants, deficient in rnh201.
创建时间：
2019-09-18
