CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB698223
收藏NIAID Data Ecosystem2026-05-02 收录
数据链接:
官方服务:
资源简介:
CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB698223
应用场景:
创建时间:
2024-05-08
相关数据集
Speeding up Early Drug Discovery in Antiviral Research: A Fragment-Based in Silico Approach for the Design of Virtual Anti-Hepatitis C Leads
Hepatitis C constitutes an unresolved global health problem. This infectious disease is caused by the hepatotropic hepatitis C virus (HCV), and it can lead to the occurrence of life-threatening medica
NIAID Data Ecosystem60
Structure of the genotype 2B HCV polymerase
Structure of the genotype 2B HCV polymerase Descriptor: RNA-directed RNA polymerase Authors: Rydberg, E.H, Carfi, A. Deposit date: 2009-03-27 Release date: 2009-07-07 Last modified: 2026-03-04 Method:
Protein Data Bank Japan2026-03-04 更新50
HCV NS5B GT1A with GSK5852
HCV NS5B GT1A with GSK5852 Descriptor: HCV Polymerase, SULFATE ION, [4-({[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl](methylsulfonyl)amino}methyl)-2-fluorophenyl]boronic ac
Protein Data Bank Japan2024-03-13 更新30
The index of ideality of correlation: QSAR studies of hepatitis C virus NS3/4A protease inhibitors using SMILES descriptors
Robust and reliable QSAR models were developed to predict half-maximal inhibitory concentration (IC50) values of hepatitis C virus NS3/4A protease inhibitors from the Monte Carlo technique. 524 HCV NS
NIAID Data Ecosystem50
A Cell-Based Assay for RNA Synthesis by the HCV Polymerase Reveals New Insights on Mechanism of Polymerase Inhibitors and Modulation by NS5A
RNA synthesis by the genotype 1b hepatitis C virus (HCV) polymerase (NS5B) transiently expressed in Human embryonic kidney 293T cells or liver hepatocytes was found to robustly stimulate RIG-I-depende
NIAID Data Ecosystem30



