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Using Barcode system in the CRISPR screening.
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创建时间：
2020-07-01
相关数据集
Table_DepMap2018Q4_JACKS_pvalue.txt
DepMap 2018 Q4 data processed with JACKS (pvalue)
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VSV-LACV HAP1 human surfacesome Crisp Screen sequence reads
To identify host cell factors required for LACV entry, we used a lentiviral library of 4,630 single guide RNAs targeting 1,146 human genes that encode proteins predicted to be present on the plasma me
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Raw sgRNA count data.
Sample information for raw count sgRNA data in S9–S12 Data for genetic screens performed in this work. sgRNA, single gRNA. (XLSX)
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Additional file 12 of Identification of functional regulatory elements in the human genome using pooled CRISPR screens
Additional file 12: Table S7. CRISPR screen raw read counts (Peak Library/dCas9-KRAB).
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Targeting SUMO2 reverses aberrant epigenetic rewiring driven by SS18::SSX fusion oncoproteins and impairs sarcomagenesis [CRISPR Screening]
Synovial sarcoma (SySa) is an aggressive soft tissue sarcoma with an urgent need to develop targeted therapies. Here, we exploited specific vulnerabilities created by transcriptional rewiring by the f
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