Crystal structure of Cryptosporidium hominis CPSF3 in complex with Compound 61

Crystal structure of Cryptosporidium hominis CPSF3 in complex with Compound 61 Descriptor: 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-trien-5-yl]propanoic acid, Cleavage and Polyadenylation Specificity Factor 3 (CPSF3), GLYCEROL, ... Authors: Palencia, A, Swale, C. Deposit date: 2018-12-07 Release date: 2019-11-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection. Sci Transl Med, 11, 2019人隐孢子虫（Cryptosporidium hominis）CPSF3与化合物61的复合晶体结构 描述项：3-[7,7-二羟基-8-氧杂-7-硼杂双环[4.3.0]壬-1(6),2,4-三烯-5-基]丙酸、剪切与多聚腺苷酸化特异性因子3（Cleavage and Polyadenylation Specificity Factor 3，CPSF3）、甘油（GLYCEROL）…… 作者：Palencia, A.、Swale, C. 存放日期：2018-12-07 发布日期：2019-11-20 最后修改日期：2024-01-24 实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2 Å） 引用文献：《CPSF3介导的金属捕获抑制pre-mRNA加工活性控制隐孢子虫感染》，《科学·转化医学》（Sci Transl Med），11卷，2019年