Crystal structure of NDM-1 bound to hydrolyzed meropenem representing an EI2 complex
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of NDM-1 bound to hydrolyzed meropenem representing an EI2 complex Descriptor: (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, Metallo-beta-lactamase NDM-1, SULFATE ION, ... Authors: Feng, H, Liu, W, Wang, D. Deposit date: 2017-11-02 Release date: 2018-02-21 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.12 Å) Cite: The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis. Nat Commun, 8, 2017
创建时间:
2017-11-02



