Cryo-EM structure of human Ptch1 with three mutations L282Q/T500F/P504L
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Cryo-EM structure of human Ptch1 with three mutations L282Q/T500F/P504L Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein patched homolog 1 Authors: Yan, N, Gong, X, Qian, H.W. Deposit date: 2018-06-05 Release date: 2018-07-11 Last modified: 2025-05-14 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural basis for the recognition of Sonic Hedgehog by human Patched1. Science, 361, 2018
携带L282Q、T500F、P504L三处突变的人源Ptch1蛋白冷冻电镜(Cryo-EM)结构 描述组分:2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖(2-acetamido-2-deoxy-beta-D-glucopyranose)、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖(2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose)、patched同源蛋白1(Protein patched homolog 1) 作者:Yan, N, Gong, X, Qian, H.W. 提交日期:2018年6月5日 发布日期:2018年7月11日 最后修改日期:2025年5月14日 检测方法:电子显微镜(分辨率4.1埃) 引用文献:《人源Patched1识别音猬因子的结构基础》,《科学》,第361卷,2018年



