Concise Total Syntheses of (±)-Strychnine and (±)-Akuammicine
收藏NIAID Data Ecosystem2026-03-06 收录
数据链接：
官方服务：
资源简介：
Concise total syntheses of Strychnos alkaloids strychnine (1) and akuammicine (2) have been realized in 13 and 6 operations, respectively. Key steps include (1) the vinylogous Mannich reaction; (2) a novel, sequential one-pot spirocyclization/intramolecular aza-Baylis−Hillman reaction; and (3) a Heck cyclization. The synthesis of 1 proceeds via the Wieland−Gumlich aldehyde (26).
创建时间：
2010-05-21
