Highly Efficient and Expedient Synthesis of 5-Hydroxy-1<i>H</i>-pyrrol-2-(5<i>H</i>)-ones from FeCl<sub>3</sub>-Catalyzed Tandem Intramolecular Enaminic Addition of Tertiary Enamides to Ketones and 1,3-Hydroxy Rearrangement
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Catalyzed by FeCl3 under very mild conditions, tertiary enamides underwent a highly efficient intramolecular enaminic addition reaction to the ketonic carbonyls followed by 1,3-hydroxy rearrangement to produce 5-hydroxy-1H-pyrrol-2(5H)-ones in excellent yields.
创建时间：
2010-09-03
