小鼠抑瘤实验原始、分析与检测数据

选择C57BL/6J雄性小鼠进行H22细胞株的肝原位注射，注射1周后随机分组给药，共分6组，分别尾静脉注射葡萄糖注射液、奥沙利铂注射液以及载药或不载药的微纳机器人，在注射微纳机器人的4组中，对其中2组进行磁控靶向。连续给药5天，并在治疗后第10天处死取肿瘤组织，对肿瘤组织进行称重、测量和统计，通过组间比较，计算抑瘤率。Male C57BL/6J mice were selected for orthotopic liver injection with H22 cell line. One week post-injection, the mice were randomly assigned into 6 groups. The groups were treated via tail vein injection as follows: two groups received glucose injection and oxaliplatin injection respectively; the remaining four groups were administered with micro-nanorobots, including drug-loaded and unloaded formulations, with 2 of these 4 micro-nanorobot groups undergoing magnetic targeting. Drug administration was performed consecutively for 5 days. On the 10th day after the end of treatment, the mice were sacrificed, and their tumor tissues were harvested. The tumor tissues were then weighed, measured and statistically analyzed, and the tumor inhibition rate was calculated through inter-group comparative analysis.

搜集汇总

背景与挑战

背景概述

该数据集来源于一项小鼠抑瘤实验，涉及对C57BL/6J雄性小鼠进行H22细胞株肝原位注射后，分组给予葡萄糖注射液、奥沙利铂注射液及载药或不载药的微纳机器人（部分组别进行磁控靶向），连续给药5天并在治疗后第10天收集肿瘤组织进行称重、测量和统计分析，以计算抑瘤率。数据包括原始、分析与检测内容，支持'靶向药物输送场控微纳机器人精准化技术与医用基础研究'项目，总数据量为557.45MB，包含5个文件。