A role for condensin in mediating transcriptional adaptation to environmental stimuli.
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Transcriptional adaptation drives utrophin upregulation in Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a muscle-degenerating disease caused by mutations in DMD/dystrophin. Utrophin (UTRN), the functional paralog of DMD, is upregulated in DMD nonsense alleles, sugges
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Induction of a transcriptional adaptation response via perturbations at the DNA and RNA levels [dst233]. Induction of a transcriptional adaptation response via perturbations at the DNA and RNA levels [dst233]
Transcriptional adaptation (TA) is a cellular process whereby mRNA-destabilizing mutations lead to the transcriptional upregulation of so-called adapting genes. The nature of the TA-triggering factor(
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Induction of a transcriptional adaptation response by RNA destabilization events [dst278]. Induction of a transcriptional adaptation response by RNA destabilization events [dst278]
Transcriptional adaptation (TA) is a cellular process whereby mRNA-destabilizing mutations lead to the transcriptional upregulation of so-called adapting genes. The nature of the TA-triggering factor(
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A role for condensin in mediating transcriptional adaptation to environmental stimuli.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
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Cloning and RT-qPCR oligos.
Genetic robustness can be achieved via several mechanisms including transcriptional adaptation (TA), a sequence similarity-driven process whereby mutant mRNA degradation products modulate, directly or
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