Quantification of dye coupling in <i>Cx47<sup>+/M282T</sup></i>, <i>Cx47<sup>M282T/M282T</sup></i>, and <i>Cx47</i><sup>−/−</sup> mice in comparison to <i>Cx47<sup>+/+</sup></i> at P10–P15.
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Networks are shown as percentage of biocytin-injected oligodendrocytes found coupled to at least one adjacent cell. *** p<0.001 Cx47+/M282T versus Cx47+/+; Chi Square Test. Data regarding the extent of tracer spread are reported as average ± SEM; * p<0.05 Cx47−/− versus Cx47+/+; One way ANOVA followed by Bonferroni post hoc test, p<0.05. Quantification of the number of coupled cells is indicated as median (25th–75th percentiles). *** p<0.001 Cx47M282T/M282T versus Cx47+/+; Mann-Whitney U-test, Kruskal-Wallis test, p = 0.001. *** p<0.001 Cx47−/− versus Cx47+/+; Mann-Whitney U-test, Kruskall-Wallis test, p<0.001. Quantification of the population of coupled cells (CNPase+, CNPase−/GFAP−, GFAP+, eGFP+, eGFP−/GFAP−) is indicated as median (25th–75th percentiles). ** p<0.01 Cx47M282T/M282T versus Cx47+/+; Mann-Whitney U-test, Kruskal-Wallis test, p<0.01. * p<0.05 Cx47M282T/M282T versus Cx47+/+; Mann-Whitney U-test, Kruskal-Wallis test, p<0.01. *** p<0.001 Cx47−/− versus Cx47+/+; Mann-Whitney U-test, Kruskall-Wallis test, p<0.001. (n), number of experiments.
