Slco1b2
收藏rgd.mcw.edu2025-03-22 收录
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=69300
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资源简介:
ENCODES a protein that exhibits bile acid transmembrane transporter activity; oligopeptide transmembrane transporter activity; organic anion transmembrane transporter activity; INVOLVED IN bile acid and bile salt transport; liver development; oligopeptide transport; PARTICIPATES IN multispecific organic anion transporter mediated transport pathway; docetaxel pharmacodynamics pathway; mycophenolic acid pharmacokinetics pathway; ASSOCIATED WITH abnormal xenobiotic pharmacokinetics; ASSOCIATED WITH Animal Hepatitis; cholestasis; Hereditary Hyperbilirubinemia; FOUND IN basolateral plasma membrane; basal plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
编码一种具有胆汁酸跨膜转运蛋白活性的蛋白质;寡肽跨膜转运蛋白活性;有机阴离子跨膜转运蛋白活性;参与胆汁酸及胆盐的转运;肝脏发育;寡肽转运;参与多特异性有机阴离子转运蛋白介导的转运途径;多西他赛药效学途径;麦考酚酸药代动力学途径;与异常外来物药代动力学相关;与动物肝炎、胆汁淤积、遗传性高胆红素血症相关;存在于基底侧质膜;基底层质膜(同源);质膜(同源);与(+)五味子素B、1-萘基异硫氰酸酯、17α-乙炔基雌二醇相互作用。
提供机构:
Rat Genome Database



