AdipoR1/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axis
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资源简介：
Nonalcoholic steatohepatitis (NASH) and associated liver fibrosis have limited therapy options. We report a novel adiponectin-based dual agonist for adiponectin receptors 1 and 2 with a longer half-life, and show that it ameliorates NASH and liver fibrosis in mouse models. Mice liver mRNA profiles of control, NASH, and NASH with JT003 treatment mice; oil-treated control, fibrosis with CCl4 or JT003 treatment mice. Submitter declares raw data files are unavailable for the oil-treated control, fibrosis with CCl4 or JT003 treatment mice.
创建时间：
2020-12-01
