Chromatin factors assessed for AC invasion contribution (see excel file).

270 chromatin regulating factors targeted by RNAi for AC invasion defects. n≥30 animals for each RNAi clone. For each RNAi clone tested, the corresponding genetic sequence name, public name, protein annotation, and human homolog (HUGO Gene Nomenclature) from www.wormbase.com is given. Penetrance for each invasion defects is given as the % of animals with ACs that fail to invade the BM at the P6.p 4-cell stage out of the total number of animals assessed (Block/Invasion+Partial). Partial refers to cases where an animal had a breach in the BM narrower than the width of the basolateral surface of the invading AC. Genes in bold were recovered as significant regulators of AC invasion (S2 Table). Annotations were mined from the STRING consortium www.string-db.org. Asterisks in human ortholog column denote genes with > 5 detected human orthologs, for which only the first 5 returned orthologs were listed. N.A. denotes genes for which no human ortholog exists. List is organized alphabetically based on genetic sequence name. (XLSX)