Metabolic dysfunction and drug-host-microbe interactions in the Wilson's Disease gut-liver axis

A multiomics approach was designed to reveal intestinal microbiome signatures and metabolic profiles in Wilson disease patients compared with unaffected controls. The microbiome-associated data generated in the study includes 16S rRNA-based amplicon sequencing DNA reads and genome-wide transcriptomic data derived from pure cultures of Akkermansia muciniphila.