berglund2018spatial_ST_melanoma

berglund2018spatial_ST_melanoma is a spatial transcriptomics datasets of stage III cutaneous malignant melanoma67. The published paper adapted the technology of spatial transcriptomics (ST) to melanoma lymph node biopsies and successfully sequenced the transcriptomes of over 2,200 tissue domains. There are 8 sub-datasets in berglund2018spatial_ST_melanoma with ~16000 gene expression features, which contains 4 stage III cutaneous malignant melanoma patients in duplicate. The number of spots inf each sub-dataset are 279 (mel1_rep1), 293 (mel1_rep2), 383 (mel2_rep1), 380 (mel2_rep2), 256 (mel3_rep1), 294 (mel3_rep2), 212 (mel4_rep1) and 248 (mel4_rep2). The count matrix of berglund2018spatial_ST_melanoma dataset was downloaded from https://www.spatialresearch.org/resources-published-datasets/.berglund2018spatial_ST_melanoma 是一款针对III期皮肤恶性黑色素瘤的空间转录组（spatial transcriptomics, ST）数据集[67]。该已发表论文将空间转录组技术应用于黑色素瘤淋巴结活检样本，成功完成了超过2200个组织区域的转录组测序。该数据集共包含8个子数据集，每个子数据集涵盖约16000个基因表达特征，纳入4名III期皮肤恶性黑色素瘤患者的生物学重复样本（每名患者设置2次重复）。各子数据集的测序斑点（spot）数量分别为：mel1_rep1（279）、mel1_rep2（293）、mel2_rep1（383）、mel2_rep2（380）、mel3_rep1（256）、mel3_rep2（294）、mel4_rep1（212）以及mel4_rep2（248）。该数据集的计数矩阵可从https://www.spatialresearch.org/resources-published-datasets/ 下载获取。