Single-cell Transcriptome Atlas of the Human Corpus Cavernosum

Single-cell transcriptomes of corpus cavernosum from three males with normal erections and five organic erectile dysfunction (ED) patients. Three normal tissue samples were obtained from the tumour margin of penile carcinoma resection, all patients reported good stimulated erections and early morning erections. The five ED CC tissues were obtained from biopsy samples in artificial cavernous body implantation, all the ED patients were diagnosed with organic ED rather than psychological ED by the nocturnal penile tumescence (NPT) and intracavernosal injection (ICI) tests. The DMED patients had a at least 10-year history of type 1 diabetes and had good blood glucose control before surgery.