Ion Flow Through Neural Ion Membrane: scripts and data

The scripts and data are related to the numerical implementation of a quantitative model for ion flow through neural ion channels and a validation of the underlying single ion channel flow model for gramicidin A channels. The model is based on the Poisson-Nernst-Planck (PNP) equations for ion transport and is described in the related publication in detail. <br><br> Gramicidin A:<br> A PNP based model for ion flow through single ion channels is established. We validate our results with experimental data by <a href="https://doi.org/10.1016/S0006-3495(98)77726-4">Busath et al. [1998]</a> (files "NaCl.xlsx" and "KCl.xlsx") for gramicidin A channels with NaCl and KCl solutions of different concentrations. <br><br> Quantitative Model:<br> We extend the single channel model by calibrating it with whole-cell patch clamp in-house experimental data (file "DataPatchClampIV.xlsx"). We refer to the related publication for information on the experimental setup. <br><br> See comments in the scripts for further information.