Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum

The whole transcriptome profiles of HCT-8 cells infected with C. parvum were obtained in this study. GO and KEGG pathway analyses have suggested significant roles for these dif-RNAs during the course of C. parvum infection. A ceRNA regulation network containing miRNA at its center was constructed for the first time, with hsa-miR-324-3p and hsa-miR-3127-5p being the crucial miRNAs. These findings provide novel insights into the responses of human intestinal epithelial cells against C. parvum infection.