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Effects of TNF on 'starved' primary hepatocytes

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https://www.ncbi.nlm.nih.gov/sra/SRP338610
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We generated transcriptional profiles of TNF-stimulated primary hepatocytes co-treated with PPARa and GR ligands to mimic a condition of starvation. Overall design: Primary hepatocytes were cotreated with corticosterone (GR ligand), WY-14643 (PPARa ligand), and TNF for 8 hours to assess the effect of TNF on 'starved' hepatocytes.
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2022-05-03
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