Photo-tunable Protein Nitration by Sensitizer Tris(bipyridine)-Ruthenium(II) Chloride complex_Trypsin digestion Dataset

Post-translational modifications of proteins are a diverse source of variability that impacts on their functions, localization, regulation, and lifetime; and oxidative modifications are usually associated to pathological and degenerative conditions. Photosensitizers have been employed to promote oxidative modifications and model molecular aspects of diseases. Therefore, we provide the MS/MS raw data from the application of the novel light-controlled Ru(bpy)3+2/APS/NaNO2 system to nitrate four different model proteins. Each protein dataset contains raw data from treated and untreated samples.

蛋白质的翻译后修饰是影响其功能、定位、调控和寿命的多样性变异来源；氧化修饰通常与病理性和退行性疾病相关联。光敏剂已被用于促进氧化修饰并模拟疾病的分子方面。因此，我们提供了使用新型光控 Ru(bpy)3+2/APS/NaNO2 系统对四种不同模型蛋白进行硝酸盐处理的 MS/MS 原始数据。每个蛋白质数据集包含处理前后样本的原始数据。