RNA sequencing on primary murine chondrocytes expressing mutant Idh1

NIAID Data Ecosystem2026-04-25 收录

骨相关细胞转录组

Idh1突变效应

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https://www.ncbi.nlm.nih.gov/sra/SRP171160 数据链接链接失效反馈

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We report expression of a mutant Idh1 in murine chondrocytes caused a global change in the gene expression profile. Overall design: mRNA profile of primary sternal chondrocytes from Col2a1Cre;Idh1 fl/fl mice and two control groups - Col2a1Cre and Idh1 fl/fl mice.

创建时间：

2019-09-24

Microarray of Dexamethasone-treated primary chondrocytes identifies downstream targets of glucocorticoid signalling. Mus musculus

骨相关细胞转录组

内皮素信号通路

Background: Glucocorticoids (GCs) are widely used anti-inflammatory drugs. While useful in clinical practice, patients taking GCs often suffer from skeletal side effects including growth retardation a

NIAID Data Ecosystem60

Transcriptome profile of RCS chondrocyte wt cell line and RCS chondrocyte obtained from a clone ko for the FGF receptors FGFR3 and FGFR4. Transcriptome profile of RCS chondrocyte wt cell line and RCS chondrocyte obtained from a clone ko for the FGF receptors FGFR3 and FGFR4

骨相关细胞转录组

FGF信号通路

To understand the transcriptomic effect of FGF18 treatment on Chondrocytes cells from wt rat and on Chondrocytes obtained from a clone ko for the FGF receptors FGFR3 and FGFR4, we performed Quant-seq

NIAID Data Ecosystem20

Transcription profiling of mouse dexamethasone-treated primary chondrocytes identifies downstream targets of glucocorticoid signalling

内皮素信号通路

骨相关细胞转录组

Transcription profiling of mouse dexamethasone-treated primary chondrocytes identifies downstream targets of glucocorticoid signalling

ChEBI2008-06-15 更新10

RNA-Seq based analysis of chondroblasts subjected to general caspase inhibition revealed modulation of a spectrum of osteoarthritis related genes. RNA-Seq based analysis of chondroblasts subjected to general caspase inhibition revealed modulation of a spectrum of osteoarthritis related genes

关节炎分子机制

骨相关细胞转录组

Objective: The knowledge about functions of caspases, traditionally associated with cell death and inflammation, keeps expanding also regarding cartilage. Active caspases are expressed by chondrocytes

NIAID Data Ecosystem20

Cytoplasmic polyadenylation by TENT5A is required for proper bone formation.

成骨分化分子机制

骨相关细胞转录组

The goal of this study was to assess changes in the mineralizing osteoblasts transcriptome upon TENT5A knockout in mice. Neonatal calvarial and adult long-bones osteoblasts were isolated from TENT5A K

NIAID Data Ecosystem10

RNA sequencing on primary murine chondrocytes expressing mutant Idh1

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