Foxa-deficiency Restricts Hepatitis B Virus Biosynthesis Through Epigenic Silencing
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2024-10-15
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Text S1 - The Role of Multiple Marks in Epigenetic Silencing and the Emergence of a Stable Bivalent Chromatin State
We have relegated the mathematical details of the model in Text S1. Analytical solution of the model in the mean-field limit is presented therein, and the nature of the different phases is summarized.
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Morc3 silences endogenous retroviruses in mouse embryonic stem cells [ATAC-seq]. Morc3 silences endogenous retroviruses in mouse embryonic stem cells [ATAC-seq]
Background: MORC proteins are involved in epigenetic gene silencing in a wide variety of eukaryotic organisms. Deletion of MORCs result in several developmental abnormalities and their dysregulation h
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LINE1 TGS mechanism mediated by SETDB1-AGO2 complex in human somatic cells [ChIP-seq]. LINE1 TGS mechanism mediated by SETDB1-AGO2 complex in human somatic cells [ChIP-seq]
LINE1s are abundant retroelements comprising 17% of human genome. Naturally, genomic LINE1s are tightly repressed by epigenetic mechanism; however, if relieved, they can be detrimental to genome stabi
NIAID Data Ecosystem40
RNAi-dependent Polycomb repression controls transposable elements in Tetrahymena [RNA-seq]. RNAi-dependent Polycomb repression controls transposable elements in Tetrahymena [RNA-seq]
RNA interference (RNAi) and Polycomb repression play evolutionarily conserved and often coordinated roles in transcriptional silencing. Here we show that in the protozoan Tetrahymena thermophila, germ
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Expression data from cid14 delta and air1 delta strains. Schizosaccharomyces pombe
Expression profiling of cid14 delta and air1 delta cells shows that efficient silencing of a few heterochromatic genes depends on Cid14 and/or Air1. Overall design: Gene expression in the mutants was
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