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资源简介：
Deactivation of Hepatic Stellate Cells during Liver Fibrosis Resolution in Mice
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创建时间：
2015-07-08
相关数据集
Transcriptome analysis of activated fibroblasts isolated from fibrotic livers. Transcriptome analysis of activated fibroblasts isolated from fibrotic livers
RNA-seq analysis of steady-state hepatic stllate cells and activated fibroblasts isolated from distinct liver fibrosis models; Western diet–induced NASH and carbon tetrachrolide–induced liver fibrosis
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Mus musculus domesticus Epigenomics. Mus musculus domesticus
Recent studies have revealed the importance of DNA hypermethylation in the progression of liver fibrosis to hepatocellular carcinoma (HCC). However, the importance of DNA methylation in the early-stag
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Model for the prediction of advanced fibrosis.
Cross-validation of this model adjusted p value to less than 0.0037 with following characteristics: AUC: 0.750 (CI: 0.581–0.877), Optimal sensitivity: 59.38 (CI: 40.6–76.3); Optimal specificity: 80.00
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Data for the publication "An Integrative Transcriptome Subtraction Strategy to Identify Human lncRNAs That Specifically Play a Role in Activation of Human Hepatic Stellate Cells" https://doi.org/10.3390/ncrna10030034
Fibrotic liver features excessive deposition of extracellular matrix (ECM), primarily produced from “activated” hepatic stellate cells (HSCs). While targeting human HSCs (hHSCs) in fibrosis therapeuti
DataCite Commons2024-06-24 更新130
Data of Correlation of intestinal flora and serum metabolites in NiONPs induced-liver fibrosis via metagenomics and metabonomics analysis
我们收集血清样本进行全代谢组学测序，筛选出差异代谢物。然后收集结肠粪便样本进行全宏基因组学分离，得到911892 Unigenes和优势细菌门为拟杆菌门、厚壁菌门、变形杆菌门、螺旋体门和放线菌门，还发现益生菌丰度降低，菌群酶活性变化（P<0.05）。
DataCite Commons2025-04-27 更新70
