Signalling inhibition by ponatinib disrupts alternative lengthening of telomeres (ALT)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE190438
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资源简介:
Analyses of gene expression changes in cells treated with ponatinib (experiment 1), and in cells either lacking JUN or overexpressing JUN (experiment 2). Experiment 1: RNA-seq on SAOS-2 or T1000 cells treated with either DMSO (as a control) or ponatinib (250nM for 24 hours); 2 replicates per condition. Experiment 2: Identification of potential JUN transcription targets by RNA-seq in SAOS2 cells lacking JUN (cjun sg vs. LacZ sg as a control) or overexpressing JUN (JUN vs. CTRL (GFP overexpressing cells)); 3 replicates per condition
创建时间:
2023-04-11



