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资源简介：
Transcription profiling by high throughput sequencing in castration resistant prostate cancer cell lines
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创建时间：
2025-01-24
相关数据集
Systematic characterization of epigenetic modifying enzymes identifies KDM3B as a key regulator in castration resistant prostate cancer. Systematic characterization of epigenetic modifying enzymes identifies KDM3B as a key regulator in castration resistant prostate cancer
Androgen deprivation therapy (ADT) is the standard care for prostate cancer patients who fail surgery and radiotherapy. While initially effective, the cancer almost always recurs into a more aggressiv
NIAID Data Ecosystem100
ARv7 represses tumor suppressors genes in castration-resistant prostate cancer [RNA-Seq]
Endocrine therapies in prostate cancer (PCa) treatment block androgen receptor (AR) function, but are palliative as tumors progress to a lethal, castration-resistant state (CRPC). CRPC remains depende
NIAID Data Ecosystem50
The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity. Homo sapiens
Analysis of gene expression altered upon knockdown of Siah2 in prosate cancer cells. The objective is to elucidate which signaling pathways or transcription factors are regulated by the E3 ubiquitin l
NIAID Data Ecosystem40
Additional file 1: of Abiraterone acetate for chemotherapy-naive metastatic castration-resistant prostate cancer: a single-centre prospective study of efficacy, safety, and prognostic factors
The raw data of mCRPC patients in this study. (XLSX 27 kb)
NIAID Data Ecosystem60
Bruceantin targets HSP90 to overcome resistance to hormone therapy in castration-resistant prostate cancer. Bruceantin targets HSP90 to overcome resistance to hormone therapy in castration-resistant prostate cancer
Here we report the identification of bruceantin as a highly potent inhibitor of HSP90. RNA-seq analysis demonstrated bruceantin inhibits the transcriptional activity of androgen receptor and androgen
NIAID Data Ecosystem50
