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Synthesis of 2‑Oxindoles Sharing Vicinal All-Carbon Quaternary Stereocenters via Organocatalytic Aldol Reaction

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Figshare2016-12-07 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Synthesis_of_2_Oxindoles_Sharing_Vicinal_All-Carbon_Quaternary_Stereocenters_via_Organocatalytic_Aldol_Reaction/4291595
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An organocatalytic enantioselective aldol reaction using paraformaldehyde as C1-unit has been developed for the synthesis of 2-oxindoles sharing vicinal all-carbon quaternary stereocenters. The methodology is eventually employed in the formal total synthesis of (+)-folicanthine (1b).
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2016-12-07
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