Background: Blood–brain barrier (BBB) damage is considered an important part of Alzheimer's disease (AD) progression, and cerebral small-vessel disease (CSVD) is commonly associated with AD. However,
Alzheimer's disease is a disease of neurodegeneration and aging that affects millions of Americans, and is expected to impact millions more without significant advancement in our understanding of the
Monomeric C-reactive protein (mCRP) plays a role in cerebrovascular damage mediated by apolipoprotein E4 (ApoE4) in Alzheimer's disease (AD) pathogenesis. Using proteomic profilings, we found altered
This collection of datasets is from three cohorts of mice. Mice in cohort #1 had resting-state cerebral blood flow (CBF) measured with laser speckle imaging (LSI) across different age groups (12, 18,
