EGF signaling in vulval development
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EGF signaling is a key pathway involved in vulval patterning. Vulval precursor cell patterning requires input and cooperation between both EGF LIN-3 graded signaling through LET-23 as well as a sequential, subordinate signal involving DSL ligands acting via LIN-12. See figure 8 here: http://www.wormbook.org/chapters/www_vulvaldev/vulvaldev.pdf
表皮生长因子（EGF）信号通路是参与外阴形态发生的关键途径。外阴前体细胞的形态排列需要表皮生长因子LIN-3分级信号通过LET-23的输入和协作，以及涉及DSL配体通过LIN-12作用的递进性、从属信号。请参阅图8，详情见：http://www.wormbook.org/chapters/www_vulvaldev/vulvaldev.pdf
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